The Hotel Ithaca 222 S. Cayuga St. Ithaca, NY 14850 Get Directions 222 S. Cayuga St. Ithaca, NY 14850 Get Directions 607-272-1000 thehotelithaca.com sheffron@harthotels.com View all locations Featured Partners Top-Tier Supporters of the Cayuga Lake Scenic Byway, Inc. Enjoy the Ride! Auburn Aurora Ithaca Penn Yan/Cayuga Lake Ithaca Ithaca Lansing Ithaca Aurora Trumansburg Seneca Falls Ithaca Ithaca Trumansburg Romulus Waterloo